What are the side effects of Mounjaro?

They are typically Gastrointestinal in nature, may increase as doses get titrated up, and generally go away in time. Delayed Gastric Emptying may go away eventually as well, but it does not affect the efficacy of Mounjaro.

Tips for Nausea

  • Non-Drowsy Dramamine

  • Bonine (motion sickness relief)
  • Ginger Chews or Pickled Ginger (like from sushi restaurants)
  • Peppermint chews (apparently in a tub container, available on Amazon)
  • Zofran (may cause constipation and requires a prescription, ask your doctor)
  • Pepto Bismol
  • Upspring Stomach Settle drops
  • Sniffing rubbing alcohol

Tips for Diarrhea

  • Pepto Bismol
  • Fiber 

Tips for Constipation

  • CALM magnesium gummies
  • Miralax
  • Fiber
  • Fiber Well Sugar-Free Fiber Gummies


Tips for Bloating

  • GasX
  • See if this is from constipation by trying treatments for that


Tips for Sulfur Burps


  • Charco Caps
  • Pepto Bismol
  • GasX 
  • Peppermint Gum
  • Upspring Stomach Settle drops
  • Omeprazole (Prilosec) or Pantoprazole (Protonix)
  • Activated Charcoal
  • Metoclopramide – this is in a class of medications called prokinetic agents. It works by speeding the movement of food through the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite. Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD).



Tips for Acid Reflux

  • Pantoprezole (Protonix) or Omeprazole (Prilosec) (these are PPI pills, or Proton Pump Imhibitors)
  • Pepcid AC (H2 blocker antacid pill)
  • Tums
  • Gaviscon 
  • Nexium 
  • GasX
  • Super Papaya Enzyme Plus
  • Don’t eat hours before bed
  • Lift the head of your bed a few inches
  • Yellow mustard
  • Coconut water
  • Aloe Vera juice 
  • Even though it may seem counter intuitive, some think that the lower esophageal sphincter (LES, the “doorman” muscle that prevents food from coming up into your esophagus from the stomach) is not as tight when the acid level in the stomach is actually too LOW. So under this theory is recommended that you try shots of apple cider vinegar diluted in plain glass of water, and lemon water. There are YouTube videos reviewing the use of Apple cider vinegar and ppl say they discontinued all use of prescription antacids after adopting this practice.

Nutrition Care (NC) Gut Relief Formula – a product from Australia available online. Link to an online resource: https://natonic.com.au/en/nutrition-care-gut-relief-150g. Research study below.

Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders

Nutrition Research, April 2020



Re: theories on when best to take PPI pills:

“For this reason, in the case of pantoprazole and omeprazole, since food decreases the AUC, it would be better to administer these drugs under fasting conditions. However, Iwata et al. observed that pre-dinner administration of PPIs could increase their efficacy in patients with gastroesophageal reflux disease [25].”

Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole

BMC Pharmacology and Toxicology, 2020