Tips for Acid Reflux?

By Gwynne Sullivan, Amy Nowacoski · last reviewed May 9, 2026

Adapted from the Mounjaro for Diabetes FAQ with permission from the contributing authors.

  • Pantoprezole (Protonix) or Omeprazole (Prilosec) (these are PPI pills, or Proton Pump Imhibitors)
  • Pepcid AC (H2 blocker antacid pill)
  • Tums
  • Gaviscon
  • Nexium
  • GasX
  • Super Papaya Enzyme Plus
  • Don’t eat hours before bed
  • Lift the head of your bed a few inches
  • Yellow mustard
  • Coconut water
  • Aloe Vera juice
  • Even though it may seem counter intuitive, some think that the lower esophageal sphincter (LES, the “doorman” muscle that prevents food from coming up into your esophagus from the stomach) is not as tight when the acid level in the stomach is actually too LOW. So under this theory is recommended that you try shots of apple cider vinegar diluted in plain glass of water, and lemon water. There are YouTube videos reviewing the use of Apple cider vinegar and ppl say they discontinued all use of prescription antacids after adopting this practice.
  • Nutrition Care (NC) Gut Relief Formula - a product from Australia available online. Link to an online resource: https://natonic.com.au/en/nutrition-care-gut-relief-150g. Research study below.

Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders Nutrition Research, April 2020 https://www.sciencedirect.com/science/article/pii/S027153171931187X

Re: theories on when best to take PPI pills: “For this reason, in the case of pantoprazole and omeprazole, since food decreases the AUC, it would be better to administer these drugs under fasting conditions. However, Iwata et al. observed that pre-dinner administration of PPIs could increase their efficacy in patients with gastroesophageal reflux disease [25].” Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole BMC Pharmacology and Toxicology, 2020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382816/